Crucial Challenges in the Development of Green Extraction Technologies to Obtain Antioxidant Bioactive Compounds from Agro-industrial By–Products

Exploitation of agro-industrial by-products represents an important source bioactive compounds that can be used both directly as ingredients and for the production <br /> functional ingredients. Among these compounds, polyphenols are capable strengthening endogenous antioxidant defences in human tissues, preventing cardiovascular neurodegenerative diseases. The present paper aims to evaluate review various green extraction technologies a cheap, fast, eco-friendly procedure obtain molecules. Several physicochemical approaches with aim optimizing use energy, solvents, pressure; among them ultrasound-assisted extraction, subcritical supercritical fluid neoteric solvents (ionic liquids, deep eutectic natural solvents), microwave-assisted pressurized liquid pulsed electric field, multi-frequency multimode modulated technology, rapid solid dynamic enzyme-assisted extraction. challenges future work regarding development products commercial markets were comprehensively evaluated.